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Ginkgo
biloba |
|
| CHEMICAL
COMPOSITION |
There are
two groups of important substances in Ginkgo biloba : the flavonoids and the terpenes
(ginkgolides) 1. |
| PHARMACOLOGY |
It has antioxidant and anti -
coagulant qualities. The Antioxidant action of Ginkgo has been shown to have beneficial
effects on brain neurons subjected to ischemia 2
.Ginkgo has repeatedly been shown to improve cognitive functions in humans
and laboratory animals Ginkgo has repeatedly been shown to improve cognitive functions in
humans and laboratory animals. Ginkgo biloba extract protects neuronal cell
membranes from free radical damage 3 . It was found that
Ginkgo biloba extract improved concentration and memory in elderly patients with arterial
insufficiency 4 . |
| THERAPEUTIC
USES |
Clinically important
indications for Ginkgo biloba extract include Alzheimer's disease and similar dementias,
cerebral insufficiency due to stroke, and atherosclerotic disease of the peripheral
arteries 4 . |
| REFERENCES |
- Z'Brun A. Ginkgo -Myth and
reality.Schweiz Rundsch Med Prsax 1995; 84(1):1-6. (Switzerland).
- Oyama Y, Fuchs PA, Katayama
N, Noda K. Brian Res 1994; 635(1-2):125-9. (Netherlands)
- Stoll S, Scheuer K, Pohl O,
Muller WE. Pharmacopsychiatry 1996; 29(4):144-9. (Germany)
- Draback H, Petersen JR,
WIinberg N, Hansen KF, Mehlsen J.Ugeskr Laeger 1996;158(27)3928-31 (Denmark)
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| SPECIFICATIONS: GINKGO
BILOBA EXTRACT
General
Information:
| Type of extract |
: |
Dry powder |
| Plant Parts used |
: |
Leaves |
| Source |
: |
Wild Crafted |
| Shelf life |
: |
24 months unopened |
| Storage |
: |
Keep in a cool, dry
place protected from moisture and heat |
| Active ingredient/s |
: |
Ginkgoflavone glycosides and Terpene lactones |
| Method of analysis |
: |
HPLC and GC |
Analytical
Specifications :
| Description |
: |
Light brown powder |
| Organoleptic characters |
: |
Bitter in taste with characteristic odour |
| Loss on drying |
: |
Not more than 5% W/W |
| Lead |
: |
Not more than 10 PPM |
| Arsenic |
: |
Not more than 2 PPM |
| Heavy metals |
: |
Not more than 20 PPM |
| Assay |
|
|
| a) Ginkgoflavone glycosides content on dry basis by
HPLC |
: |
Not less than 24.0% W/W |
| b) Terpene lactones content by GC |
: |
Not less than 6.0% W/W |
Microbiological Profile
Total bacterial count |
: |
Not more than 3000 CFU/gm |
| Yeasts and moulds |
: |
Not more than 100 CFU/gm |
| E.coli |
: |
Absent |
| S.aureus |
: |
Absent |
| Salmonella typhi |
: |
Absent |
| Pseudomonas aeruginose |
: |
Absent |
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