Morinda citrifolia
(Noni)

CHEMICAL COMPOSITION The fruit contains Morindin, proxeronine and the enzyme proxeronase.
PHARMACOLOGY Morindin followed by acetylcholine or vice versa, increased heart beat frequency in isolated cockroach heart. It stimulated cardiac neurons by causing acetylcholine release and did not appear to affect cholinesterase at neuromuscular junction2. When taken orally Proxeronine and Proxeronase combine in the intestine to produce xeronine. The alkaloid xeronin is physiologically very active and important for the proper function of all the cells in the body. It actually works at the molecular level to repair damaged cells. Anticancer activity of the fruit on intraperitonially implanted lewis lung carcinoma in syngenic mice was observed. It acts indirectly by enhancing host immune system involving macrophages and/or lymphocytes3. The compound damacanthal found in the fruit was found to be an inhibitor of Ras function4. The fruit showed analgesic and behavioral effects5. It is also effective against at least seven different kinds of harmful bacteria. It is a natural antiseptic. It is effective against fungus and parasites.
THERAPEUTIC USES The fruit was used for its analgesic, antiseptic, immunostimulant, anticancer and antihypertensive properties.
REFERENCES
  1. Glossary of Indian Medicinal Plants, CSIR,     New Dehi (1992)
  2. Acta Entamol. Bohemoslov. 1982, 79, 341; Chem.     Abstr. 1983, 98, 65241 x
  3. Proc. West Pharmacol. Soc. 37 : 145-146 (1994)
  4. Cancer letters 73 (1993) 161 - 166
  5. Planta Medica 56 (1990) 430 - 434
SPECIFICATIONS:

MORINDA CITRIFOLIA EXTRACT
(Noni)

General Information:

Type of extract : Thick Paste
Plant parts used : Fruits
Source : Wild crafted
Shelf life : 24 months unopened
Storage : Keep in a cool, dry place

Analytical Specifications :

Description : Dark brown coloured thick paste
Organoleptic characters : Characteristic taste and odour
Loss on drying : Not more than 5% W/W
Lead : Not more than 10 PPM
Arsenic : Not more than 2 PPM
Heavy metals : Not more than 20 PPM
Total solids : Not less than 70%
Herb to product ratio : 5:1
Microbiological profile :
Total bacterial count : Not more than 3000 CFU/gm
Yeasts and moulds : Not more than 100 CFU/gm
E.coli : Absent
S.aureus : Absent
Salmonella typhi : Absent
Pseudomonas aeruginose : Absent
* Morinda citrifolia is also available in dry powder form

 

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