|
|
 |
Neem
(Azadirachta indica) |
|
| CHEMICAL
COMPOSITION |
Contains
bitters and also quercetin and ß sitosterol glucocide1. |
| PHARMACOLOGY |
Aqueous
extract of leaves decreased blood sugar levels and prevented adrenaline as well as glucose
hyperglycaemia2. Fractions of acetone extract showed CNS
depressant, positive inotropic and blood pressure lowering activities3.
A single dose of 3gm, in human subjects was found to be highly effective and majority of
positive stool cases of ascariasis were worm and ovum free. It is found effective against
intestinal worms in farm animals4. The extract showed antifungal
activity against some soil-borne pathogens of Cicer arietinum5. |
| THERAPEUTIC
USES |
Used as
an antineoplastic and antiviral. Indicated in eczema, ringworm and scabies. Very effective
anthelmintic in ascariasis. Also mosquito larvicidal6. |
| REFERENCES |
- Shibata el al :
Ind.J.Phram., 17:230 (1955)
- Iketa T.: Nippon Kosholnin
Kagakkushu 8(1):67:(1984)
- Selected Medicinal Plants of
India, CHEMEXCIL, NewDelhi (1992)
- Hennemann,H. and G.Kunnert,
Pharmazie 8:463 (1953)
|
| SPECIFICATIONS: NEEM
EXTRACT
(Azadirachta indica)
General
Information:
| Type of extract |
: |
Dry powder |
| Plant parts used |
: |
Leaves |
| Source |
: |
Wild crafted |
| Shelf life |
: |
24 months unopened |
| Storage |
: |
Keep in a cool, dry
place protected from moisture and heat |
| Active ingredient/s |
: |
Bitters |
| Method of analysis |
: |
Gravimetry/HPTLC |
Analytical
Specifications :
| Description |
: |
Brown powder |
| Organoleptic characters |
: |
Extremely bitter
in taste with characteristic odour |
| Loss on drying |
: |
Not more than 5% W/W |
| Lead |
: |
Not more than 10 PPM |
| Arsenic |
: |
Not more than 2 PPM |
| Heavy metals |
: |
Not more than 20 PPM |
| Assay |
|
|
| Bitters content on dry basis by Gravimetry/HPTLC |
: |
Not less than 2.5% W/W |
| Microbiological profile |
|
|
| Total bacterial count |
: |
Not more than 3000 CFU/gm |
| Yeasts and moulds |
: |
Not more than 100 CFU/gm |
| E.coli |
: |
Absent |
| S.aureus |
: |
Absent |
| Salmonella typhi |
: |
Absent |
| Pseudomonas aeruginose |
: |
Absent |
|
|
