|
|
 |
Tinospora
cordifolia |
|
| CHEMICAL
COMPOSITION |
Different constituents reported include a
glucoside, alkaloids, bitter principles, crystalline components etc1.
The bitter principles have been identified as columbin, chasmanthin and palmarin2.
The alkaloid tinosporin3 was also identified. |
| PHARMACOLOGY |
Studies on induced oedema and arthritis and
on human arthritis proved antiinflammatory potency of the water extract of plant4.
It also has antipyretic action and is a morphine potentiator5.
It induced reduction in blood sugar in alloxan induced hyperglycaemic rats and rabbits6.
This drug relaxes the intestinal and uterine smooth muscles7.
Blood urea levels in uraemic dogs and human subjects were also decreased8.
It is proved effective in prevention of fibrosis and in stimulating regeneration in
hepatic tissue9. |
| THERAPEUTIC
USES |
Used for the treatment of jaundice,
rheumatoid arthritis, diabetes, gout, viral hepatitis, arthopathies and general weakness. |
| REFERENCES |
- Bisset N.G. and J.Nwaiwu, Planta Med. 48:275, 1983.
- Bhide B.v. et al: J.Univ. Bombay, 10:89, 1941.
- Kidwai, A.R. et al: J.sci.Indus.res. 813,115,1949.
- Pendse, V.K. et al: Ind.J.Phamacol 9:221(1977).
- Pendse, V.K. et al: Ind.Drugs Oct: 14(1981).
- Gulati O.D.et al: Rheumatism 17:76, 1982.
- Raghunathan, I. et al: J.Res.Med. 3:201(1969).
- Singh, K.P. et al. :J.Res.Ind.Med. 10:9(1975).
- Rege, N. et al: Ind.Drugs Sept. 544(1984).
|
| SPECIFICATIONS: TINOSPORA
CORDIFOLIA EXTRACT
General
Information:
| Type of extract |
: |
Dry powder |
| Plant parts used |
: |
Stem |
| Source |
: |
Wild crafted |
| Shelf life |
: |
24 months unopened |
| Storage |
: |
Keep in a cool, dry
place protected from moisture and heat |
| Active ingredient/s |
: |
Bitters |
| Method of analysis |
: |
Gravimetry/HPTLC |
Analytical
Specifications :
| Description |
: |
Yellowish brown powder |
| Organoleptic characters |
: |
Extremely bitter in taste |
| Loss on drying |
: |
Not more than 5% W/W |
| Lead |
: |
Not more than 10 PPM |
| Arsenic |
: |
Not more than 2 PPM |
| Heavy metals |
: |
Not more than 20 PPM |
| Assay |
|
|
| Bitters
content on dry basis by Gravimetry/HPTLC |
: |
Not less than3% W/W |
| Microbiological profile |
|
|
| Total bacterial count |
: |
Not more than 3000 CFU/gm |
| Yeasts and moulds |
: |
Not more than 100 CFU/gm |
| E.coli |
: |
Absent |
| S.aureus |
: |
Absent |
| Salmonella typhi |
: |
Absent |
| Pseudomonas aeruginose |
: |
Absent |
|
|
